What it's sold for

Weight loss
Appetite suppression

What has actually been tested

Obesity
Parkinson Disease
Alzheimer Disease
Atrial Fibrillation (AF)
Confirmed Genetic Diagnosis of Prader-Willi Syndrome
Healthy Male Subjects
Hypothalamic Injury-induced Obesity (HIO)
Hypothalamic Obesity

Is it studied for what it's sold for?

Each claim below is matched against the condition and title fields of every registered trial. Not listed means no trial names it as a studied condition — not that it has been disproven, and not that no trial touches it indirectly.

Studied Weight loss

Not listed Appetite suppression

Every trial on record

Every registered human study we can find for Tesofensine. Click any ID to read the original record — we would rather you checked us than trusted us.

Trial ID	Title	Condition	Phase	Status	Enrolled
NCT05712200	Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)	Atrial Fibrillation (AF)	Phase 3	Recruiting now	2500
NCT00153010	An Evaluation of Three Doses of NS 2330 in Patients With Mild to Moderate Dementia of the Alzheimer's Type	Alzheimer Disease	Phase 2	Completed	430
NCT00428415	Effect of Tesofensine on Energy Balance in Humans.	Obesity	Phase 2	Completed	32
NCT03149445	Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS)	Confirmed Genetic Diagnosis of Prader-Willi Syndrome	Phase 2	Completed	18
NCT00394667	Effect of Tesofensine on Weight Reduction in Patients With Obesity.	Obesity	Phase 2	Completed	200
NCT03488719	A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate	Phase 1	Phase 1	Completed	37
NCT03845075	48 Weeks, Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO)	Hypothalamic Injury-induced Obesity (HIO)	Phase 2	Completed	21
NCT02737891	Safety and Efficacy Study of Tesofensine/Metoprolol Treatment in Subjects With Type 2 Diabetes Mellitus	Type 2 Diabetes Mellitus	Phase 2	Completed	60
NCT03286829	Study to Investigate the Pharmacokinetic Profile	Healthy Male Subjects	Phase 1	Completed	60
NCT00148512	A Randomized, Double-blind, Placebo-controlled, Five Parallel Groups Efficacy and Safety Study of NS 2330 (Tesofensine) (0.125 mg, 0.25 mg, 0.5 mg and 1.0 mg) Administered Orally Once Daily Over 14 Weeks in Levodopa Treated Parkinson Patients With Motor Fluctuations	Parkinson Disease	Phase 2	Completed	254
NCT00481104	Evaluation of Long Term Safety of Tesofensine in Patients With Obesity	Obesity	Phase 2	Completed	140
NCT00148486	A Fourteen-Week Placebo-Controlled Dose-Response Efficacy and Safety Study of NS 2330 in Early Parkinson's Disease Patients (Study for Proof of Concept in Early Parkinson's Disease of a Triple Reuptake Inhibitor, NS 2330 / SCEPTRE)	Parkinson Disease	Phase 2	Completed	261
NCT05198362	Study of Tesomet With Open-label Extension in Subjects With Prader-Willi Syndrome	Prader-Willi Syndrome	Phase 2	Withdrawn before enrolling	0 — nobody enrolled
NCT05147415	Study of Tesomet With Open-label Extension in Subjects With Hypothalamic Obesity (HO)	Hypothalamic Obesity	Phase 2	Withdrawn before enrolling	0 — nobody enrolled

—Read this

A trial count is not a verdict

These numbers describe how much has been formally studied in humans, not whether something works or is safe for you. A compound can be tested for one condition and sold for another — which is usually the story. This page is automated aggregation from public registries; no physician has reviewed it. Take anything here to a clinician.

Why sources disagree on this number

Different sites publish different counts for Tesofensine because they are answering different questions. Here is every way of counting the same set of studies, so you can see which rule produces which number.

Registered human trials the number we publish

Interventional studies in people, listed on ClinicalTrials.gov, at any status.

Completed

Registered trials whose status is "completed".

Still running

Recruiting, not yet recruiting, or active.

Stopped early

Terminated, withdrawn, or suspended.

With a stated phase

Registered trials tagged Phase 1-4.

100+ participants

Registered trials enrolling at least 100 people.

Observational studies

Studies that watch rather than intervene.

You may see a lower number than 14.

Sources that count only completed studies get 11. We count registered trials at any status, because a trial that is recruiting is still a real trial and is the thing most likely to change this page. Neither number is wrong; they answer different questions.

Which number should you use?

For "how much human evidence exists", 14 is the honest answer, with the caveat that 11 have actually finished. Every trial is listed on this page with its ID — if you disagree with how we count, you can recount it yourself in about a minute.

Common questions about Tesofensine

How many human trials does Tesofensine have?

14. That is the number of registered interventional human studies we can find, each listed on this page with a link to its original record.

Is Tesofensine FDA approved?

No. Tesofensine is not approved by the FDA for any indication. Compounded or "research use only" preparations are not FDA-approved and receive no premarket review for safety, effectiveness, or manufacturing quality.

What is Tesofensine actually being tested for?

Registered studies cover: atrial fibrillation (af), alzheimer disease, obesity. Compare that to what it is marketed for — the two lists are often different, which is the whole point of this page.

Where does this data come from?

ClinicalTrials.gov, the US public registry of clinical studies. We count interventional human studies only — observational studies are not evidence of effect. Every trial on this page links to its original record so you can check us rather than trust us.