# What's Actually Known

> Independent tracker of what peptide compounds are actually being tested for in
> registered human clinical trials, versus what they are marketed for. All data
> is mirrored from ClinicalTrials.gov. We sell nothing, take no advertising, and
> accept no money from sellers or clinics.

What's Actually Known counts registered interventional human studies for each compound and
publishes that count next to the claims made by sellers. We do not grade
evidence, recommend treatments, or give dosing advice — we report what is on
the public record and link to it.

Last checked against ClinicalTrials.gov: 2026-07-27

## Method

- Source: ClinicalTrials.gov public API
- Counted: interventional human studies only (observational studies are not
  evidence of effect and would inflate every number)
- Not counted: animal studies, in-vitro work, unregistered research
- No medical judgment is applied. There is no grade, score, or rating.
- This is automated aggregation. No physician has reviewed these pages.

## About this project

An independent research project. Not affiliated with any seller, clinic,
pharmacy, supplement company, or research institution.

Editorial position: this project reports what is registered and does not
evaluate evidence. There is no grade, score, or rating anywhere on the site.
Counting registered trials is a factual operation that can be independently
verified; judging whether evidence is good is a clinical judgment, and no
physician reviews these pages. That limit is disclosed on every compound page.

Maintenance: a scheduled job mirrors the ClinicalTrials.gov public API and
regenerates affected pages. Counts are recomputed from stored records rather
than edited. Every page carries the date its data was last checked.

Manual review covers search terms, which are the known failure mode. Example:
TB-500 initially matched 18 trials because the query also caught "Thymosin
Beta-4" — the full protein, a different molecule from the fragment sold as
TB-500. Publishing that count would have overstated its human evidence
eighteenfold. The query was narrowed and the mis-attributed trials removed.

Funding: no products, affiliate links, sponsorship, advertising, or money from
sellers, clinics or pharmacies. Any change will be disclosed at the top of every
page.

- [Who runs this](https://www.whatsactuallyknown.com/about)
- [How we count](https://www.whatsactuallyknown.com/method)
- [What we are and what we're not](https://www.whatsactuallyknown.com/why-trust-us)

## Compounds

- [Selank](https://www.whatsactuallyknown.com/compounds/selank): Selank has no registered human trials in the registries we track. Marketed for: Anxiety, Cognitive enhancement, Focus, Stress resilience.
- [Hexarelin](https://www.whatsactuallyknown.com/compounds/hexarelin): Hexarelin has no registered human trials in the registries we track. Marketed for: Muscle growth, Cardiac protection, Anti-aging.
- [AOD-9604](https://www.whatsactuallyknown.com/compounds/aod-9604): AOD-9604 has no registered human trials in the registries we track. Marketed for: Fat loss, Weight management, Cartilage repair.
- [GHRP-6](https://www.whatsactuallyknown.com/compounds/ghrp-6): GHRP-6 has no registered human trials in the registries we track. Marketed for: Muscle growth, Fat loss, Recovery, Appetite / bulking.
- [Epitalon](https://www.whatsactuallyknown.com/compounds/epitalon): Epitalon has no registered human trials in the registries we track. Marketed for: Telomere lengthening, Longevity / lifespan extension, Sleep & circadian repair.
- [GHRP-2](https://www.whatsactuallyknown.com/compounds/ghrp-2): GHRP-2 has no registered human trials in the registries we track. Marketed for: Muscle growth, Fat loss, Sleep quality, Anti-aging.
- [5-Amino-1MQ](https://www.whatsactuallyknown.com/compounds/5-amino-1mq): 5-Amino-1MQ has no registered human trials in the registries we track. Marketed for: Fat loss, Metabolic health, Longevity, Muscle preservation.
- [Semax](https://www.whatsactuallyknown.com/compounds/semax): Semax has no registered human trials in the registries we track. Marketed for: Cognitive enhancement, Focus & memory, Stroke recovery, Anxiety.
- [CJC-1295](https://www.whatsactuallyknown.com/compounds/cjc-1295): CJC-1295 has 1 registered human trial. Marketed for: Muscle growth, Fat loss, Anti-aging via growth hormone, Sleep quality.
- [TB-500](https://www.whatsactuallyknown.com/compounds/tb-500): TB-500 has 1 registered human trial. Marketed for: Soft-tissue & tendon recovery, Injury healing, Hair growth.
- [Melanotan II](https://www.whatsactuallyknown.com/compounds/melanotan-2): Melanotan II has 1 registered human trial. Marketed for: Tanning without sun, Libido, Appetite suppression.
- [BPC-157](https://www.whatsactuallyknown.com/compounds/bpc-157): BPC-157 has 2 registered human trials. Marketed for: Tendon & ligament repair, Gut healing / "leaky gut", Systemic anti-aging, Injury recovery.
- [Ipamorelin](https://www.whatsactuallyknown.com/compounds/ipamorelin): Ipamorelin has 2 registered human trials. Marketed for: Muscle gain, Fat loss, Recovery & sleep, Anti-aging.
- [GHK-Cu](https://www.whatsactuallyknown.com/compounds/ghk-cu): GHK-Cu has 3 registered human trials. Marketed for: Skin repair & anti-aging, Hair growth, Wound healing.
- [MOTS-c](https://www.whatsactuallyknown.com/compounds/mots-c): MOTS-c has 5 registered human trials. Marketed for: Metabolic health, Endurance & performance, Longevity.
- [PT-141](https://www.whatsactuallyknown.com/compounds/pt-141): PT-141 has 10 registered human trials. Marketed for: Libido / sexual function, Erectile function, Energy.
- [Thymosin β4](https://www.whatsactuallyknown.com/compounds/thymosin-beta-4): Thymosin β4 has 18 registered human trials. Marketed for: Tissue repair, Wound healing, Hair growth, Cardiac recovery.
- [Tesamorelin](https://www.whatsactuallyknown.com/compounds/tesamorelin): Tesamorelin has 21 registered human trials. Marketed for: Visceral fat loss, Anti-aging, Cognition.
- [Retatrutide](https://www.whatsactuallyknown.com/compounds/retatrutide): Retatrutide has 33 registered human trials. Marketed for: Weight loss, Blood sugar control, Metabolic health.
- [Sermorelin](https://www.whatsactuallyknown.com/compounds/sermorelin): Sermorelin has 34 registered human trials. Marketed for: Anti-aging, Muscle & body composition, Sleep, Energy.
- [Thymosin α1](https://www.whatsactuallyknown.com/compounds/thymosin-alpha-1): Thymosin α1 has 63 registered human trials. Marketed for: Autoimmune conditions, Immune system regulation, Chronic infection, Longevity / immune aging.
- [Tirzepatide](https://www.whatsactuallyknown.com/compounds/tirzepatide): Tirzepatide has 234 registered human trials. Marketed for: Weight loss, Blood sugar control.
- [Semaglutide](https://www.whatsactuallyknown.com/compounds/semaglutide): Semaglutide has 610 registered human trials. Marketed for: Weight loss, Blood sugar control, Cardiovascular risk.

## Newsletter

- [The weekly read](https://www.whatsactuallyknown.com/archive): what moved in the research each week,
  and which claims the record does not support.
- [Issue 1: GHRP-6 is sold for 4 things. It has been tested for none.](https://www.whatsactuallyknown.com/archive/issue-001)

## Common questions, answered

Direct factual answers, one URL each. Only questions the registry can answer —
no "is it safe" or "should I take it", which require a clinician.

- [All questions](https://www.whatsactuallyknown.com/questions)
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-5-amino-1mq-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-aod-9604-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-bpc-157-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-cjc-1295-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-epitalon-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-ghk-cu-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-ghrp-2-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-ghrp-6-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-hexarelin-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-ipamorelin-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-melanotan-2-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-mots-c-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-pt-141-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-retatrutide-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-selank-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-semaglutide-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-semax-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-sermorelin-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-tb-500-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-tesamorelin-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-thymosin-alpha-1-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-thymosin-beta-4-have
- https://www.whatsactuallyknown.com/questions/how-many-human-trials-does-tirzepatide-have
- https://www.whatsactuallyknown.com/questions/is-5-amino-1mq-fda-approved

## Key lists

- [The full register — every compound with its trial count](https://www.whatsactuallyknown.com/compounds)
- [Peptides with zero registered human trials](https://www.whatsactuallyknown.com/zero-trial-peptides)
- [Compounds with studies recruiting now](https://www.whatsactuallyknown.com/currently-recruiting)
- [Which of these are FDA approved](https://www.whatsactuallyknown.com/fda-approved-peptides)

## Method and policy

- [How we count and what we exclude](https://www.whatsactuallyknown.com/method)
- [Corrections policy](https://www.whatsactuallyknown.com/corrections)
- [Privacy](https://www.whatsactuallyknown.com/privacy)

## Full data

- [llms-full.txt](https://www.whatsactuallyknown.com/llms-full.txt): every compound and every trial as plain text.
- [sitemap.xml](https://www.whatsactuallyknown.com/sitemap.xml)

## What we do not publish

- Dosing, protocols, or stacks
- Claims that a compound works or does not work
- Reasons a trial stopped, unless the registry states one
- Anything we cannot link to a primary source