Compounds / Tesamorelin

Tesamorelin

Egrifta

Tesamorelin has 21 registered human trials — it is genuinely well studied. The question worth asking is what those trials were studying, because it is often not what the compound is sold for.

In short

  • 21 registered human trials exist for Tesamorelin.
  • No registered trial lists anti-aging as a studied condition.
  • Tesamorelin is FDA-approved — but only for a specific indication, not general use.
  • What has actually been studied: metabolic associated steatotic liver disease, nonalcoholic steatohepatitis.
  • 3 studies are open to new participants, so this may change.
  • Last checked against ClinicalTrials.gov on 2026-07-27.
21
Registered human trials
3
Recruiting or running
Yes
FDA approved
Pre
P1
P2
P3
Furthest stage reached

FDA-approved for HIV-associated lipodystrophy.

What it's sold for

  • Visceral fat loss
  • Anti-aging
  • Cognition

What has actually been tested

  • Abdominal Obesity
  • HIV
  • Mild Cognitive Impairment
  • Aging
  • Growth Hormone Deficiency
  • HIV Infections
  • HIV Lipodystrophy
  • Lipodystrophy

Is it studied for what it's sold for?

Each claim below is matched against the condition and title fields of every registered trial. Not listed means no trial names it as a studied condition — not that it has been disproven, and not that no trial touches it indirectly.

Studied Visceral fat loss
Not listed Anti-aging
Studied Cognition

Every trial on record

Every registered human study we can find for Tesamorelin. Click any ID to read the original record — we would rather you checked us than trusted us.

Trial IDTitleConditionPhaseStatusEnrolled
NCT07481734 Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study) Metabolic Associated Steatotic Liver Disease, Nonalcoholic Steatohepatitis Phase 2 Recruiting now 120
NCT03150511 Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury Peripheral Nerve Injuries Phase 2 Recruiting now 36
NCT06554717 Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV HIV-1-infection, Frailty Phase 2 Recruiting now 100
NCT00608023 TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy Lipodystrophy, HIV Infections Phase 3 Completed 263
NCT02553603 The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment Mild Cognitive Impairment Phase 1 Completed 22
NCT00675506 Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese Abdominal Obesity, Growth Hormone Deficiency Phase 2 Completed 60
NCT01264497 Safety Study of TH9507 in Subjects With Stable, Type 2 Diabetes Type 2 Diabetes Phase 2 Completed 55
NCT00850564 Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men Healthy Volunteers Not phased Completed 15
NCT00257712 SMART: Somatotrophics, Memory, and Aging Research Trial Aging, Mild Cognitive Impairment Phase 2 Completed 151
NCT02012556 Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive Patients HIV Phase 1 Completed 18
NCT03375788 Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk Non-Alcoholic Fatty Liver Disease, Obesity Phase 2 Completed 51
NCT00123253 TH9507 in Patients With HIV-Associated Lipodystrophy HIV Infections, Lipodystrophy Phase 3 Completed 412
NCT01263717 Effects of Growth Hormone Releasing Hormone in HIV HIV, HIV Lipodystrophy Not phased Completed 54
NCT00795210 Effects of Short-term Growth Hormone in HIV-infected Patients HIV Lipodystrophy Not phased Completed 25
NCT02196831 Tesamorelin Effects on Liver Fat and Histology in HIV Human Immunodeficiency Virus (HIV), Nonalcoholic Fatty Liver Disease (NAFLD) Not phased Completed 61
NCT02572323 Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected Persons Mild Cognitive Impairment Phase 2 Completed 73
NCT03226821 Body Composition and Adipose Tissue in HIV HIV Lipodystrophy Syndrome, Growth Hormone Deficiency Phase 4 Stopped early 6
NCT01591902 Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA® Diabetic Retinopathy, HIV Phase 4 Stopped early 129
NCT01388920 Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting Chronic Obstructive Pulmonary Disease (COPD) Phase 2 Stopped early 3
NCT01632592 Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone Analogue Abdominal Obesity Not phased Withdrawn before enrolling 0 — nobody enrolled
NCT02931474 Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia Sleep Disorder, Traumatic Brain Injury Phase 2 Withdrawn before enrolling 0 — nobody enrolled
Read this
A trial count is not a verdict
These numbers describe how much has been formally studied in humans, not whether something works or is safe for you. A compound can be tested for one condition and sold for another — which is usually the story. This page is automated aggregation from public registries; no physician has reviewed it. Take anything here to a clinician.

Common questions about Tesamorelin

How many human trials does Tesamorelin have?

21. That is the number of registered interventional human studies we can find, each listed on this page with a link to its original record.

Is Tesamorelin FDA approved?

Yes, but read the detail: FDA-approved for HIV-associated lipodystrophy. An approval for one condition is not an approval for everything it is marketed for.

What is Tesamorelin actually being tested for?

Registered studies cover: metabolic associated steatotic liver disease, nonalcoholic steatohepatitis, hepatic steatosis. Compare that to what it is marketed for — the two lists are often different, which is the whole point of this page.

Where does this data come from?

ClinicalTrials.gov, the US public registry of clinical studies. We count interventional human studies only — observational studies are not evidence of effect. Every trial on this page links to its original record so you can check us rather than trust us.

Get told when this changes

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