Compounds / Sermorelin

Sermorelin

GHRH (1-29)

Sermorelin has 34 registered human trials — it is genuinely well studied. The question worth asking is what those trials were studying, because it is often not what the compound is sold for.

In short

  • 34 registered human trials exist for Sermorelin.
  • No registered trial lists anti-aging or energy as a studied condition.
  • Sermorelin is not FDA-approved for any use.
  • What has actually been studied: metabolic associated steatotic liver disease, nonalcoholic steatohepatitis.
  • 3 studies are open to new participants, so this may change.
  • Last checked against ClinicalTrials.gov on 2026-07-27.
34
Registered human trials
3
Recruiting or running
No
FDA approved
Pre
P1
P2
P3
Furthest stage reached

Was FDA-approved for pediatric growth hormone deficiency; withdrawn from the US market in 2008 for commercial reasons, not safety.

What it's sold for

  • Anti-aging
  • Muscle & body composition
  • Sleep
  • Energy

What has actually been tested

  • Growth Hormone Deficiency
  • Abdominal Obesity
  • Aging
  • Obesity
  • HIV
  • HIV Infections
  • HIV Lipodystrophy
  • Lipodystrophy

Is it studied for what it's sold for?

Each claim below is matched against the condition and title fields of every registered trial. Not listed means no trial names it as a studied condition — not that it has been disproven, and not that no trial touches it indirectly.

Not listed Anti-aging
Studied Muscle & body composition
Studied Sleep
Not listed Energy

Every trial on record

Every registered human study we can find for Sermorelin. Click any ID to read the original record — we would rather you checked us than trusted us.

Trial IDTitleConditionPhaseStatusEnrolled
NCT07481734 Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study) Metabolic Associated Steatotic Liver Disease, Nonalcoholic Steatohepatitis Phase 2 Recruiting now 120
NCT06701071 Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation Infertility, Female Phase 4 Recruiting now 120
NCT06554717 Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV HIV-1-infection, Frailty Phase 2 Recruiting now 100
NCT01359488 VRS-317 in Adult Subjects With Growth Hormone Deficiency Growth Hormone Deficiency Phase 1 Completed 50
NCT00608023 TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy Lipodystrophy, HIV Infections Phase 3 Completed 263
NCT02553603 The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment Mild Cognitive Impairment Phase 1 Completed 22
NCT00675506 Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese Abdominal Obesity, Growth Hormone Deficiency Phase 2 Completed 60
NCT01264497 Safety Study of TH9507 in Subjects With Stable, Type 2 Diabetes Type 2 Diabetes Phase 2 Completed 55
NCT00850564 Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men Healthy Volunteers Not phased Completed 15
NCT03018886 Diagnosing Adult Growth Hormone Deficiency Growth Hormone Deficiency Not phased Completed 160
NCT01060488 Comparative Validation of the Growth Hormone Releasing Hormone and Arginine Test for the Diagnosis of Adult Growth Hormone Deficiency Growth Hormone Deficiency Phase 3 Completed 69
NCT00000380 Growth Hormone Releasing Hormone (GHRH) Treatment for Age-Related Sleep Disturbances Sleep Disorders Not phased Completed
NCT00257712 SMART: Somatotrophics, Memory, and Aging Research Trial Aging, Mild Cognitive Impairment Phase 2 Completed 151
NCT02012556 Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive Patients HIV Phase 1 Completed 18
NCT03375788 Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk Non-Alcoholic Fatty Liver Disease, Obesity Phase 2 Completed 51
NCT00791843 The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart Failure Congestive Heart Failure Phase 2 Completed 3
NCT00123253 TH9507 in Patients With HIV-Associated Lipodystrophy HIV Infections, Lipodystrophy Phase 3 Completed 412
NCT01263717 Effects of Growth Hormone Releasing Hormone in HIV HIV, HIV Lipodystrophy Not phased Completed 54
NCT01701973 Effect of DPP4 Inhibition on Growth Hormone Secretion Obesity Phase 4 Completed 44
NCT02271282 Estradiol-Receptor Blockade in Older Men and Women Normal Healthy Volunteers Phase 1 Completed 40
NCT00795210 Effects of Short-term Growth Hormone in HIV-infected Patients HIV Lipodystrophy Not phased Completed 25
NCT02196831 Tesamorelin Effects on Liver Fat and Histology in HIV Human Immunodeficiency Virus (HIV), Nonalcoholic Fatty Liver Disease (NAFLD) Not phased Completed 61
NCT00324064 Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing Growth Hormone Deficiency Not phased Completed 90
NCT03031535 Study of Intranasal Octreotide (DP1038) in Healthy Adult Volunteers Healthy Volunteer Study Phase 1 Completed 32
NCT01897844 A Two Part Phase 1, Repeated Doses and Continuous Infusion Study With ITF2984 in Healthy Volunteers Healthy Phase 1 Completed 36
NCT00448747 Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test. Diagnosis of Adult Growth Hormone Deficiency (AGDH) Phase 3 Completed 101
NCT03226821 Body Composition and Adipose Tissue in HIV HIV Lipodystrophy Syndrome, Growth Hormone Deficiency Phase 4 Stopped early 6
NCT00720902 Adult Growth Hormone Deficiency and Cardiovascular Risk Growth Hormone Deficiency Phase 4 Stopped early 7
NCT01237041 Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children Obesity, Short Stature Phase 2 Stopped early 37
NCT02736591 Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian Response Subfertility Phase 3 Status not updated 210
NCT01632592 Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone Analogue Abdominal Obesity Not phased Withdrawn before enrolling 0 — nobody enrolled
NCT00807365 Six Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the Elderly Elderly Phase 2 Stopped early 5
NCT01410799 Three Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the Elderly Hormone Deficiency, Aging Phase 2 Stopped early 13
NCT02931474 Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia Sleep Disorder, Traumatic Brain Injury Phase 2 Withdrawn before enrolling 0 — nobody enrolled
Read this
A trial count is not a verdict
These numbers describe how much has been formally studied in humans, not whether something works or is safe for you. A compound can be tested for one condition and sold for another — which is usually the story. This page is automated aggregation from public registries; no physician has reviewed it. Take anything here to a clinician.

Common questions about Sermorelin

How many human trials does Sermorelin have?

34. That is the number of registered interventional human studies we can find, each listed on this page with a link to its original record.

Is Sermorelin FDA approved?

No. Sermorelin is not approved by the FDA for any indication. Compounded or "research use only" preparations are not FDA-approved and receive no premarket review for safety, effectiveness, or manufacturing quality.

What is Sermorelin actually being tested for?

Registered studies cover: metabolic associated steatotic liver disease, nonalcoholic steatohepatitis, hepatic steatosis. Compare that to what it is marketed for — the two lists are often different, which is the whole point of this page.

Where does this data come from?

ClinicalTrials.gov, the US public registry of clinical studies. We count interventional human studies only — observational studies are not evidence of effect. Every trial on this page links to its original record so you can check us rather than trust us.

Get told when this changes

One email a week: what moved in the research, and which claims the record doesn't support. Free, and you can leave in one click.