Compounds / PT-141

PT-141

Bremelanotide · Vyleesi

PT-141 has 10 registered human trials on record. It is marketed for 3 different uses.

In short

  • 10 registered human trials exist for PT-141.
  • No registered trial lists libido / sexual function, erectile function or energy as a studied condition.
  • PT-141 is FDA-approved — but only for a specific indication, not general use.
  • What has actually been studied: sexual arousal disorder, hypoactive sexual desire disorder.
  • No study is currently open to new participants.
  • Last checked against ClinicalTrials.gov on 2026-07-27.
10
Registered human trials
1
Recruiting or running
Yes
FDA approved
Pre
P1
P2
P3
Furthest stage reached

FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women. Grey-market "PT-141" is not the approved product.

What it's sold for

  • Libido / sexual function
  • Erectile function
  • Energy

What has actually been tested

  • Hypoactive Sexual Desire Disorder
  • Female Sexual Arousal Disorder
  • Kidney Disease
  • Lactating Mother
  • Nausea
  • Obesity
  • Sexual Arousal Disorder

Is it studied for what it's sold for?

Each claim below is matched against the condition and title fields of every registered trial. Not listed means no trial names it as a studied condition — not that it has been disproven, and not that no trial touches it indirectly.

Not listed Libido / sexual function
Not listed Erectile function
Not listed Energy

Every trial on record

Every registered human study we can find for PT-141. Click any ID to read the original record — we would rather you checked us than trusted us.

Trial IDTitleConditionPhaseStatusEnrolled
NCT00425256 Evaluate the Safety and Efficacy of Bremelanotide in Women With Female Sexual Arousal Disorder (FSAD) Sexual Arousal Disorder Phase 2 Completed
NCT04943068 A Phase 3, Bridging, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder (With or Without Decreased Arousal) Hypoactive Sexual Desire Disorder Phase 3 Completed 193
NCT06867835 Single Dose of Vyleesi in Lactating Female Subjects to Measure the Concentration of Bremelanotide in Breast Milk Lactating Mother Phase 4 Completed 10
NCT02338960 2. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder Hypoactive Sexual Desire Disorder Phase 3 Completed 714
NCT01382719 Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder Female Sexual Arousal Disorder, Hypoactive Sexual Desire Disorder Phase 2 Completed 612
NCT03973047 Study to Evaluate Rate of Nausea in Healthy Premenopausal Female Subjects Treated With Single Dose of Bremelanotide Alone or With Zofran Nausea Phase 1 Completed 228
NCT02333071 1. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder Hypoactive Sexual Desire Disorder Phase 3 Completed 723
NCT05709444 A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease Kidney Disease Phase 2 Completed 16
NCT04179734 Role of the Melanocortin-4 Receptor in Hypoactive Sexual Desire Disorder Hypoactive Sexual Desire Disorder Phase 4 Completed 40
NCT06565611 A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity Obesity Phase 2 Running, closed to new participants 108
Read this
A trial count is not a verdict
These numbers describe how much has been formally studied in humans, not whether something works or is safe for you. A compound can be tested for one condition and sold for another — which is usually the story. This page is automated aggregation from public registries; no physician has reviewed it. Take anything here to a clinician.

Common questions about PT-141

How many human trials does PT-141 have?

10. That is the number of registered interventional human studies we can find, each listed on this page with a link to its original record.

Is PT-141 FDA approved?

Yes, but read the detail: FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women. Grey-market "PT-141" is not the approved product. An approval for one condition is not an approval for everything it is marketed for.

What is PT-141 actually being tested for?

Registered studies cover: sexual arousal disorder, hypoactive sexual desire disorder, lactating mother. Compare that to what it is marketed for — the two lists are often different, which is the whole point of this page.

Where does this data come from?

ClinicalTrials.gov, the US public registry of clinical studies. We count interventional human studies only — observational studies are not evidence of effect. Every trial on this page links to its original record so you can check us rather than trust us.

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