What it's sold for

Metabolic health
Endurance & performance
Longevity

What has actually been tested

Aminoglycoside Toxicity
Bilateral Vestibular Deficiency
Bilateral Vestibular Hypofunction
Bilateral Vestibulopathy
Breast Cancer
Chronic Kidney Disease
Gentamicin Ototoxicity
Insulin Resistance

Is it studied for what it's sold for?

Each claim below is matched against the condition and title fields of every registered trial. Not listed means no trial names it as a studied condition — not that it has been disproven, and not that no trial touches it indirectly.

Not listed Metabolic health

Not listed Endurance & performance

Not listed Longevity

Every trial on record

Every registered human study we can find for MOTS-c. Click any ID to read the original record — we would rather you checked us than trusted us.

Trial ID	Title	Condition	Phase	Status	Enrolled
NCT07438002	Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment	Chronic Kidney Disease	Not phased	Recruiting now	50
NCT06500975	Long Term Outcomes After Vestibular Implantation	Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency	Not phased	Recruiting now	32
NCT07505745	MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity	Prediabetes, Insulin Resistance	Phase 2	Recruiting now	120
NCT07678073	Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal Transplantation	Kidney Disease, End-Stage, Kidney Transplant	Not phased	Recruiting now	68
NCT04013568	Exercise Post-Diagnosis of Breast Cancer	Breast Cancer	Not phased	Completed	62

—Read this

A trial count is not a verdict

These numbers describe how much has been formally studied in humans, not whether something works or is safe for you. A compound can be tested for one condition and sold for another — which is usually the story. This page is automated aggregation from public registries; no physician has reviewed it. Take anything here to a clinician.

Common questions about MOTS-c

How many human trials does MOTS-c have?

5. That is the number of registered interventional human studies we can find, each listed on this page with a link to its original record.

Is MOTS-c FDA approved?

No. MOTS-c is not approved by the FDA for any indication. Compounded or "research use only" preparations are not FDA-approved and receive no premarket review for safety, effectiveness, or manufacturing quality.

What is MOTS-c actually being tested for?

Registered studies cover: chronic kidney disease, bilateral vestibular hypofunction, bilateral vestibular deficiency. Compare that to what it is marketed for — the two lists are often different, which is the whole point of this page.

Where does this data come from?

ClinicalTrials.gov, the US public registry of clinical studies. We count interventional human studies only — observational studies are not evidence of effect. Every trial on this page links to its original record so you can check us rather than trust us.